XLR11 & Fluoroalkyl Analogs

NameXLR11 & Fluoroalkyl Analogs
Formal Name(1-​(5-​fluoropentyl)-​1H-​indol-​3-​yl)(2,​2,​3,​3-​tetramethylcyclopropyl)methanone
SMILESFCCCCCN1C=C(C(C2C(C)(C)C2(C)C)=O)C3=C1C=CC=C3
InChI KeyPXLDPUUMIHVLEC-UHFFFAOYSA-N
InChI CodeInChI=1S/C21H28FNO/c1-20(2)19(21(20,3)4)18(24)16‐14‐23(13‐9‐5‐8‐12-22)17‐11‐7‐6‐10‐15(16)17/h6‐7,10‐11,14,19H,5,8‐9,12‐13H2,1‐4H3
DescriptionXLR11 is tetramethylcyclopropylethanoyl indole analog of AM2201 which is a known abused synthetic cannabinoid1,2 and specifically listed in the Synthetic Drug Control Act of 2011.3 It is related to UR‐144 and other structurally similar compounds described in a patent from Abbott Laboratories4 which had been originally developed as CB2 receptor ligands for the treatment of pain. A recent epidemiological report associates acute kidney injury with XLR‐11 exposure.5 The fluoroalkyl analogs of XLR11 are also expected to have similar biological activity to XLR11 and may be substituted to evade detection in crime labs.

Status

Verified
Submitted2013-04-30
Submitted ByCayman Chemical
Defense Forensic Science Center, United States Army Criminal Investigation Laboratory (USACIL), Forest Park, Georgia
Published2013-05-20
ContactPaul D. Kennedy, PhD. at Cayman Chemical
Product DetailsLink

Monograph

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