PB-22

NamePB-22
Formal Name1-​pentyl-​8-​quinolinyl ester-​1H-​indole-​3-​carboxylic acid
SMILESO=C(OC1=C(N=CC=C2)C2=CC=C1)C3=CN(CCCCC)C4=C3C=CC=C4
InChI KeyZAVGICCEAOUWFM-UHFFFAOYSA-N
InChI CodeInChI=1S/C23H22N2O2/c1-2-3-6-15-25-16-19(18-11-4-5-12-20(18)25)23(26)27-21-13-7-9-17-10-8-14-24-22(17)21/h4-5,7-14,16H,2-3,6,15H2,1H3
DescriptionPB‐22 and 5‐fluoro‐PB‐22 are novel synthetic cannabinoids recently detected in Japanese herbal blends.1 No previous literature exists on the use of these compounds as cannabimimetics and their origin is unknown. Structurally, PB‐22 and 5F‐PB‐22 are similar to JWH‐018 and AM2201 respectively, two of the most common first and second generation abused synthetic cannabinoids. Both contain an N‐alkylindole moiety however the napthylacyl group has been replaced by a quinolinyl ester. Biological and toxicological data has not been reported for these compounds. It has been observed in our lab that these compounds will slowly degrade when stored in alcohol solvents at room temperature (via transesterification). Acetonitrile or other aprotic solvents are recommended to be used with this structural class of compounds.

Status

Verified
Submitted2013-05-21
Submitted ByCayman Chemical
Florida Department of Law Enforcement, Pensacola Regional Operations Center
Published2013-08-14
ContactPaul D. Kennedy, PhD. at Cayman Chemical
Product DetailsLink

Monograph

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